GeneAb™

Actin, Smooth Muscle

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Cat. No.

IHC506-100

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Description

Actin is part of the cytoskeletal system of all cell types. Smooth Muscle Actin is found in myofibroblasts and myoepithelium, but not in cardiac and skeletal muscles. Labelling of smooth muscle actin in concert with muscle specific actin staining can allow for differentiation between rhabdomyosarcoma and leiomyosarcoma, as Muscle specific actin is found in rhabdomyoblasts, while smooth muscle actin is found in leiomyosarcomas.

Specifications

Clone IHC506
Source Mouse Monoclonal
Positive Control Appendix, Uterus, Vessel Wall
Dilution Range 1:100 - 1:200

References

  1. Cooke PH. J Cell Biol. 1976; 68:539-556.
  2. Gown AM, et al. J Cell Biol. 1985; 100:807- 813.
  3. Lazarides E. J Histochem Cytochem. 1975; 223:507-528.