GeneAb™

CD79a

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$165.00

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Cat. No.

IHC079-100

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Description

Cluster of differentiation 79a (CD79a) is a molecule that dimerizes with CD79b to form the B-cell antigen receptor complex that enables antigen presentation. CD79a is specifically expressed in B lineage cell lines including early progenitors, pre-B and mature B cell lines, normal resting B lymphocytes, and polyclonally activated B cell blasts. Since Anti-CD79a and Anti-CD20 both react positively with lymphomas in many of the same cases, Anti-CD79a is frequently used in conjunction with Anti-CD20. In comparison to CD20, CD79a has a greater likelihood of staining plasma cell myeloma and some endothelia. CD79a also frequently stains acute promyelocytic leukemia (FAB-M3), but infrequently stains other types of myeloid leukemia.

Specifications

Clone IHC079
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Seda V, et al. Eur J Haematol. 2005; 94:193–205.
  2. Sakaguchi N, et al. EMBO J. 1988; 7: 3457–64.
  3. Mason DY, et al. Blood. 1995; 86:1453-9.
  4. Pilozzi E, et al. J Pathol. 1998; 186:140-3.