GeneAb™

Cyclin D1

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Cat. No.

IHC552-100

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Description

Cyclin D1 is an essential cell cycle regulator and proto-oncogene. Cyclin D1 staining is a useful tool for investigating cell cycle biology and related cancers. Anti-Cyclin D1 is used for differentiating mantle cell lymphomas (positive stain) from CLL/SLL and follicular lymphomas (negative stain). Hairy cell leukemia and plasma cell myeloma also react lightly to Anti-Cyclin D1.

Specifications

Clone IHC552
Source Mouse Monoclonal
Positive Control Mantle Cell Lymphoma
Dilution Range 1:100 - 1:200

References

  1. Aagaard L, et al. Int J Cancer. 1995; 61:115-120.
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  5. Lukas J, et al. Mol Cell Biol. 1995; 15:2600-11.
  6. Mankin RC, et al. Arch Pathol Lab Med. 1999; 123:1182-8.
  7. Yatabe Y, et al. Blood. 2000; 95:2253-61.
  8. Kodet R, et al. Virchows Arch. 2003; 442:538-47.
  9. Hui P, et al. Leuk Lymphoma. 2003; 44:1385-94.