Cyclin D1

(In the pipeline)

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Cyclin D1 is an essential cell cycle regulator and proto-oncogene. Cyclin D1 staining is a useful tool for investigating cell cycle biology and related cancers. Anti-Cyclin D1 is used for differentiating mantle cell lymphomas (positive stain) from CLL/SLL and follicular lymphomas (negative stain). Hairy cell leukemia and plasma cell myeloma also react lightly to Anti-Cyclin D1.
  • References
    1. Aagaard L, et al. Int J Cancer. 1995; 61:115-120.
    2. Bartkova J, et al. Cancer Res. 1995; 55:949-56.
    3. Bartkova J, et al. Oncogene. 1995; 10:775-8.
    4. Bartkova J, et al. J Pathol. 1994; 172:237-45.
    5. Lukas J, et al. Mol Cell Biol. 1995; 15:2600-11.
    6. Mankin RC, et al. Arch Pathol Lab Med. 1999; 123:1182-8.
    7. Yatabe Y, et al. Blood. 2000; 95:2253-61.
    8. Kodet R, et al. Virchows Arch. 2003; 442:538-47.
    9. Hui P, et al. Leuk Lymphoma. 2003; 44:1385-94.


Clone IHC552
Source Mouse Monoclonal
Positive Control Mantle Cell Lymphoma
Dilution Range 1:50-1:200