GeneAb™

DOG1

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$100.00

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Cat. No.

IHC562-100

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Description

DOG1, also known as Discovered on GIST-1, is a marker that highly specific for gastrointestinal stromal tumor (GIST). Anti-DOG1 is extremely sensitive for the detection of GIST and its diagnosis. Although some GIST stain weakly for c-kit, DOG1 is expressed in the vast majority of GIST cases. Reports have also indicated DOG1 as a marker for salivary acinar and intercalated duct differentiation.

Specifications

Clone IHC562
Source Mouse Monoclonal
Positive Control Gastrointestinal Stromal Tumor
Dilution Range 1:100 - 1:200

References

  1. Espinosa I, et al. Am J Surg Pathol. 2008; 32:210-8.
  2. Miwa S, et al. J Gastroenterol. 2008; 43:531-7.
  3. Parfitt JR, et al. Histopathology. 2008; 52:816-23.
  4. West RB, et al. Am J Pathol. 2004; 165:107-13.
  5. Lopes LF, et al. Appl Immunohistochem Mol Morphol. 2010; 18:333-7.
  6. Chênevert J, et al. Mod Pathol. 2012; 25:919-29.