GeneAb™

EMA

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$75.00

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Cat. No.

IHC566-100

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Description

Epithelial Membrane Antigen (EMA) is a mucin glycoprotein expressed on apical epithelial cells. Anti-EMA positively stains normal and neoplastic cells including sweat glands, mammary epithelia, and squamous epithelia. Adrenal carcinoma, seminomas, paraganglioma, hepatocellular carcinoma, and embryonal carcinomas exhibit a negative stain. As Anti-EMA commonly reacts positively with meningioma, it is useful for differentiating it from other intracranial neoplasms such as schwannomas.

Specifications

Clone IHC566
Source Mouse Monoclonal
Positive Control Breast, Skin
Dilution Range 1:100 - 1:200

References

  1. Pincus GS, et al. Hum Pathol. 1985; 16:929-40.
  2. Pincus GS, et al. Am J Clin Pathol. 1986; 77:269-77.
  3. Dearnaly DP, et al. Br J Cancer. 1981; 44:85-90.
  4. Redding WH, et al. Lancet. 1983; 1271-4.
  5. Attanoos RL, et al. Histopathology. 2003; 43:231-8.
  6. Beer TW, et al. Histopathology. 2000; 37:218-23.
  7. Lee JS, et al. Acta Cytol. 1996; 40:631-6.
  8. Fraga M, et al. Am J Clin Pathol. 1995; 103:82-9.