GeneAb™

Laminin

(In the pipeline)

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$100.00

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Cat. No.

IHC612-100

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Description

Laminins are a family of glycoproteins that comprise a major portion of the basal lamina of the extracellular matrix. These proteins are fundamental in early embryonic development and organogenesis, and are critical for many physiological functions associated with muscle, nerves, skin, kidney, lung, and the vasculature. Reports have indicated a number of human congenital diseases associated with laminin chain mutations, including congenital muscular dystrophy type 1A, junctional epidermolysis bullosa, cardiomyopathy, and Pierson syndrome.

Specifications

Clone IHC612
Source Mouse Monoclonal
Positive Control Skin
Dilution Range 1:100 - 1:200

References

  1. Durbeej M. Cell Tissue Res. 2010; 339:259-68.
  2. Timpl R, et al. J Biol Chem. 1979; 254:9933-7.