GeneAb™

Oct-2

(In the pipeline)

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$130.00

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Cat. No.

IHC642-100

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Description

Octamer transcription factor-2 (Oct-2) is a member of the POU homeodomain family of transcription factors. It binds to the immunoglobin gene octamer motif, thereby regulating B-cell-specific gene expression and transcription in a variety of tissues. Oct-2 is expressed highly in germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells, thus making Anti-Oct-2 useful for detecting various lymphomas including B-chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, T-cell rich B-cell lymphoma, nodular lymphocyte predominant Hodgkin’s lymphoma, and classic Hodgkin’s lymphoma.

Specifications

Clone IHC642
Source Mouse Monoclonal
Positive Control Tonsil, Lymph Node
Dilution Range 1:100 - 1:200

References

  1. Browne P, et al. Am J Clin Pathol. 2003; 120:767-77.
  2. García-Cosío M, et al. Mod Pathol. 2004; 17:1531-8.
  3. Gibson SE, et al. Am J Clin Pathol. 2006; 126:916-24.
  4. Hallermann C, et al. J Am Acad Dermatol. 2007; 56:588-97.
  5. Staudt LM, et al. Nature. 1986; 323:640-3.
  6. Scheidereit C, et al. Cell. 1987; 51:783-93.
  7. Herr W, et al. Genes Dev. 1995; 9:1679-93.
  8. Pfisterer P, et al. Mol Cell Biol. 1996; 16:6160-8.
  9. Torlakovic E, et al. Am J Pathol. 2001; 159:1807-14.
  10. Slack GW, et al. Leuk Lymphoma. 2009; 50:937-43.
  11. McCune RC, et al. Mod Pathol. 2006; 19:1010-8.
  12. Re D, et al. Cancer Res. 2001; 61:2080-4.