GeneAb™

Tau

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$130.00

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Cat. No.

IHC696-100

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Description

Tau proteins are abundant in neurons of the central nervous system, and function in microtubule stability and organization. Defects in Tau functioning and aggregation of these proteins have been clinically linked to a number of neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, Pick’s disease (PiD), progressive supranuclear palsy (PSP), cortical basal degeneration (CBD), and frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17).

Specifications

Clone IHC696
Source Mouse Monoclonal
Positive Control Thyroid Gland
Dilution Range 1:100 - 1:200

References

  1. Nuobo G, et al. Ann Diagn Pathol. 2017; 25:24-9.
  2. Espinoza M, et al. J Alzheimers Dis. 2008; 14:1-16.
  3. Goedert M, et al. Proc Natl Acad Sci U S A. 1988; 85:4051-5.
  4. Shin RW, et al. Lab Invest. 1991; 64:693-702.