GeneAb™

p53

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$125.00

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Cat. No.

IHC053-100

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Description

p53, also known as tumor protein 53 or TP53, is a tumor suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumors, including those of the breast, ovarian, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.

Specifications

Clone IHC053
Source Mouse Monoclonal
Positive Control Colon Carcinoma
Dilution Range 1:100 - 1:200

References

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