Cytokeratin 19 (CK19) forms intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue and provides mechanical support. Anti-Cytokeratin 19 stains epithelia and epithelial malignancies such as carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Cytokeratin 19 is a useful marker for distinguishing hepatocellular carcinoma from intrahepatic cholangiocarcinoma. This differentiation is improved when stained in combination with Cytokeratin 7, CAM5.2l, Ber-EP4/MOC31, HepPar1 and TTF1. Cytokeratin 19 staining can also be used to recognize thyroid papillary carcinomas.
0.1 ml Concentrate - IHC019-100
1.0 ml Concentrate - IHC019-1
7.0 ml Pre-Dilute - IHC019-7
Source Mouse Monoclonal Positive Control Bladder, Colon Carcinoma, Colon, Thyroid Carcinoma Dilution Range 1:50-1:200
- Jain R, et al. Appl Immunohistochem Mol Morphol. 2010; 18:9-15.
- Rosai J. Tumori. 2003; 89:517-9.
- de Matos LL, et al. Diagn Pathol. 2012; 7:97.