Description

p53, also known as tumor protein 53 or TP53, is a tumor suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumors, including those of the breast, ovarian, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.

p53

SKU: IHC053
  • Available Formats:

    0.1 ml Concentrate - IHC053-100

    1.0 ml Concentrate - IHC053-1

    7.0 ml Pre-Dilute - IHC053-7

     

    Clone

    IHC053

    Source Mouse Monoclonal
    Positive Control
    Colon Carcinoma
    Dilution Range 1:50-1:200

     

    1. Stoehlmacker J, et al. Oncol. 2003; 30:10-16.
    2. Gallo O, et al. Hum Pathol. 2002; 33:708-714.
    3. Sano H, et al. Cancer Res. 1995: 55:3785-9.
    4. Denkert C, et al. Cancer. 2003; 97:2978-87.
    5. Sheehan KM, et al. Hum Pathol. 2003; 34:1242-1246.
    6. Moore BE, et al. Appl Immunohistochem Mol Morphol. 2001; 9:203-6.
    7. Mauri FA, et al. Int J Oncol. 1999; 15:1137-47.
    8. Caffo O, et al. Clin Cancer Res. 1996; 2:1591-9.
    9. Bebenek M, et al. Anticancer Res. 1998; 18:619-23.
    10. Midulla C, et al. Anticancer Res. 1999; 19:4033-7.
    11. Zen ZS, et al. J Clin Oncol. 1994; 12:2043-50.
    12. Quinlan DC, et al. Cancer Res. 1992; 53:4828-31.
    13. Alexiev BA, et al. Gen Diagn Pathol. 1997; 142:271-9.

Follow Us

  • Facebook - White Circle
  • Twitter - White Circle
  • Instagram - White Circle

Subscribe to receive our latest promotions and updates

Contact Us

#1 - 3691 Viking Way

Richmond, BC V6V 2J6

[email protected]

[email protected]

[email protected]

(604) 244-9962

Copyright © 2019 GenomeMe