S-100 is a low-molecular weight protein that is found in Schwann cells, melanocytes, glial cells, histiocytes, lipocytes, skeletal and cardiac muscle, chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. S-100 is a useful marker for Schwann cell-derived tumors, as well as a number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue. Anti-S-100 is used to detect melanomas, histiocytosis X, malignant peripheral nerve sheath tumors, and clear cell sarcomas.


  • Available Formats:

    0.1 ml Concentrate - IHC100-100

    1.0 ml Concentrate - IHC100-1

    7.0 ml Pre-Dilute - IHC100-7




    Source Mouse Monoclonal
    Positive Control Melanoma
    Dilution Range 1:50-1:200


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    4. Yaziji H, et al. Int J Surg Pathol. 2003; 11:11-5.
    5. Patel P, et al. J Am Acad Dermatol. 2002; 46:264-70.
    6. Patel P, et al. J Am Acad Dermatol. 2002; 46:264-70.
    7. Morrison CD, et al. Semin Diagn Pathol. 2000; 17:204-15.
    8. McLaren KM, et al. Hum Pathol. 1996; 27:633-6.

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