T-cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.


  • Available Formats:

    0.1 ml Concentrate - IHC003-100

    1.0 ml Concentrate - IHC003-1

    7.0 ml Pre-Dilute - IHC003-7




    Source Mouse Monoclonal
    Positive Control Tonsil
    Dilution Range 1:50-1:200


    1. Monney L, et al. Nature. 2002; 415:536-41.
    2. Sánchez-Fueyo A, et al. Nat Immunol. 2003; 4:1093-101.
    3. Anderson AC. Cancer Immun Res. 2014; 2:393–8.
    4. Gao X, et al. PLoS One. 2012; 7:e30676.

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