ATRX is involved in the remodeling of the nucelosome structure, and facilitate the transcription and replication. ATRX loss occurs in grades II/III astrocytomas and glioblastomas and comes together with IDH1 mutations. Detection of ATRX with IHC acts a sensitive method to identify the mutations.

• ATRX Datasheet IVRD

• MSDS

CLONE:
IHC703

ISOTYPE:


HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Glioma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR