Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, and mediates the transport of bile acid, taurocholate, and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life.

• IHC518-BSEP Datasheet-IVD

• MSDS

CLONE:
IHC518

ISOTYPE:
IgG1

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Liver

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVD