![GeneAb™ Beta-Catenin [IHC516] on Colon Cancer](/images/product/original/Beta-Catenin-IHC516-Colon-Cancer.jpg)
GeneAb™ Beta-Catenin [IHC516] on Colon Cancer
β-Catenin is a cytoplasmic protein with a dual role in cell-cell adhesion and gene expression. It is normally present in the submembranous regions of the cell, and nuclear accumulation of β-Catenin has been found to occur as a result of gene mutations. This accumulation is useful in identifying desmoid tumours (fibromatosis) in the abdomen and breast, and is therefore useful in differentiating other cell neoplasms in these regions.
CLONE:
IHC516
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Fibromatosis of Breast
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR