Cluster of Differentiation 10 (CD10) is a cell surface metalloendopeptidase that cleaves and inactivates several peptide hormones including glucagon, enkephalins, and oxytocin. Also known as Common Acute Lymphoblastic Leukemia Antigen (CALLA), it is an important cell surface marker in the diagnosis of human ALL (Acute Lymphocytic Leukemia), and is found positive in precursor B lymphoblastic leukemia/lymphoma, angioimmunoblastic T-cell lymphoma, Burkitt's lymphoma, and follicular germinal center lymphoma. CD10 expression has also been reported in a variety of non-hematolymphoid tissues, particularly of the kidney. It is a useful aid in the diagnosis of various malignant tumours such as renal cell carcinoma, endometrial stromal sarcoma, and hepatocellular carcinoma.

• CD10 Datasheet IVDR

• MSDS

CLONE:
IHC525

ISOTYPE:
IgG1

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Kidney, Lymph Node, Tonsil

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR