Cluster of Differentiation 22 (CD22) is a glycoprotein that appears on the cell membrane of B-cells and the cytoplasm of late pro- and early pre-B-lymphocytes. Anti-CD22 is a useful pan-B reagent that allows for the identification of neoplastic and normal B-lymphocytes in the peripheral blood. CD22 is overexpressed in hairy cell leukemia. Expression is only present in the late stages of B-lymphocyte differentiation, and therefore may support the identification of mature B-cell leukemia. Some studies have suggested that CD22 may be involved in metastasis of lung cancer cells.

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• MSDS

CLONE:
IHC022

ISOTYPE:


HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR