![GeneAb™ CD79a [IHC079] on Tonsil](/images/product/original/CD79a-IHC079-Tonsil.jpg)
GeneAb™ CD79a [IHC079] on Tonsil
Cluster of Differentiation 79a (CD79a) is a molecule that dimerizes with CD79b to form the B-cell antigen receptor complex that enables antigen presentation. CD79a is specifically expressed in B lineage cell lines including early progenitors, pre-B and mature B-cell lines, normal resting B-lymphocytes, and polyclonally activated B-cell blasts. Since Anti-CD79a and Anti-CD20 both react positively with lymphomas in many of the same cases, Anti-CD79a is frequently used in conjunction with Anti-CD20. In comparison to CD20, CD79a has a greater likelihood of staining plasma cell myeloma and some endothelia. CD79a also frequently stains acute promyelocytic leukemia (FAB-M3), but infrequently stains other types of myeloid leukemia.
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CLONE:
IHC079
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Tonsil
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR