CDK4 controls cell growth during the cell cycle G1 phase. It is reported that D-type cyclin upregulates Cdk4 activity, whereas binding to the Cdk inhibitor p16 downregulates Cdk4 activity. Cyclin D-CDK4 complexes integrates various mitogenenic and antimitogenic signals and serves as sensitive and specific for atypical lipomatous tumor / well differentiated liposarcoma or dedifferentiated liposarcoma.

• IHC077-CDK4 Datasheet-RUO

• MSDS

CLONE:
IHC077

ISOTYPE:


HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Liposarcoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
RUO