Desmin is a type III intermediate filament present in normal smooth, skeletal, and cardiac muscle cells. Analysis by light microscopy suggests desmin localizes towards the periphery of Z-lines in striated muscle fibrils. Desmin connects cytoplasmic dense bodies to membranous dense plaques in smooth muscles. Anti-Desmin stains rhabdomyomas, leiomyosarcoma, rhabdomyosarcoma, leiomyomas, and perivascular cells from skin glomus tumours, and is used to identify the myogenic characteristics of tumours. Desmin can also be found in myofibroblasts and desmoid fibromatosis.

• Desmin Datasheet

• MSDS

CLONE:
IHC561

ISOTYPE:
IgG1, kappa

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Skeletal Muscle

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR