![GeneAb™ Desmoglein-3 [IHC083] on Skin Cancer](/images/product/original/Desmoglein-3-IHC083-Skin.jpg)
GeneAb™ Desmoglein-3 [IHC083] on Skin Cancer
Desmoglein-3 Antibody (DSG3) is a component of desmosomes in vertebrate epithelial cells. It identifies pulmonary squamous cell carcinomas from other types of lung cancer with high specificity and sensitivity. Studies show the upregulation of DSG3 correlated with metastasis in a number of cancers including lung cancers. The expression of DSG3 indicates a poor prognosis and portends a more aggressive clinical outcome.
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CLONE:
IHC083
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Skin Cancer
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR