Factor XIIIa(FXIIIa), also known as activated Factor XIII, is a blood coagulation factor that stabilizes fibrin and is present in monocytes, macrophages, platelets, megakaryocytes, dermal dendritic cells, and fibroblast-like mesenchymal or histiocytic cells in the placenta. Anti-Factor XIIIa is useful for distinguishing between dermatofibrosarcoma protuberans (±), dermatofibroma (mostly +), and desmoplastic malignant melanoma (-). Hemangioendothelioma, hemangiopericytoma, capillary hemagioblastoma, hepatocellular carcinoma, glomus tumour, xanthogranuloma, xanthoma, and meningioma all stain positively with Anti-Factor XIIIa.
CLONE:
IHC572
ISOTYPE:
HOST SPECIES:
Rabbit
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Placenta, Dermatofibroma
DILUTION RANGE:
INTENDED USE/REG. STATUS:
RUO