Receptor tyrosine-protein kinase erbB-3, also known as HER-3 (Human Epidermal Growth Factor Receptor 3), is a membrane bound protein and has been shown to bind the ligands heregulin and NRG-2. During human development, HER-3 antibody is expressed in skin, bone, muscle, nervous system, heart, lungs, and intestinal epithelium and is expressed in normal adult human gastrointestinal tract, reproductive system, skin, nervous system, urinary tract, and endocrine system. HER-3 is overexpressed in a variety of tumors including breast, stomach, pancreas, and colon, and is a reliable marker for aiding in the diagnosis of various cancers by immunohistochemistry.

• IHC113-Her3 Datasheet-RUO

• MSDS

CLONE:
IHC113

ISOTYPE:


HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Breast Cancer

DILUTION RANGE:


INTENDED USE/REG. STATUS:
RUO