LMO2, also known as LIM-Only Transcription Factor 2, RBTN2, or TTG2, is an oncoprotein that is expressed in normal germinal center B-cells, as well as bone marrow hematopoietic precursors and endothelial cells. LMO2 plays a role in angiogenesis and hematopoesis, and its expression has been detected in erythroid and myeloid precursors, megakaryocytes, and also in lymphoblastic and acute myeloid leukemias. LMO2 protein expression has been noted in diffuse large B-cell lymphoma, the most common adult non-Hodgkin's lymphoma, as well as follicular lymphoma, a neoplasm derived from germinal center B-cells that accounts for a number of cases of non-Hodgkin's lymphomas.

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• MSDS

CLONE:
IHC615

ISOTYPE:
IgG1, kappa

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil, Follicular Lymphoma, Diffuse Large B-Cell Lymphoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
RUO