![GeneAb™ MSH6 [IHC006] on Colon](/images/product/original/MSH6-IHC006-Colon.jpg)
GeneAb™ MSH6 [IHC006] on Colon
MutS Homolog 6 (MSH6) is a protein involved in the mismatch repair pathway. This protein is commonly associated with hereditary non-polyposis colorectal cancer, and mutations in this gene are correlated with the development of sporadic colorectal carcinoma. Studies have shown that mutations in MSH6, when co-indicated with mutations in MSH1 and MSH2, contribute to the development of sporadic colorectal carcinoma. Use of Anti-MSH2 is optimized when paired with MSH6, MLH1, and PMS2 in an IHC panel.
CLONE:
IHC006
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Colon Cancer
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR