Multiple Myeloma Oncogene-1 (MUM1), also known as Interferon Regulatory Factor 4 (IRF4), is a transcription factor present in a variety of hematolymphoid neoplasms and in malignant melanoma, but is absent from other human tumours. MUM1 expression has been indicated in both pediatric and adult diffuse large B-cell lymphoma (DLBCL), and, when the immunostaining status of CD10 and Bcl6 is also considered, Anti-MUM1 can be used to sub-distinguish germinal center type DLBCL from the non-germinal center type. Anti-MUM1 stains normal melanocytes, melanocytic nevi, and malignant melanoma in non-hematopoietic tissues, and can also stain other B-cell lymphomas such as lymphoplasmacytic lymphoma, grade 3 follicular lymphoma, primary central nervous system lymphoma, primary mediastinal large B-cell lymphoma, Burkitt-like lymphoma, and classic Hodgkin's lymphoma.

• IHC627-MUM1 Datasheet-IVD

• MSDS

CLONE:
IHC627

ISOTYPE:
IgG1

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil, Diffuse Large B-Cell Lymphoma, Plasmacytoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVD