Myogenic Differentiation 1 (MyoD1) belongs to a family of myogenic helix-loop-helix transcription factors, and, when combined with myogenin, plays a key role in the myogenic or muscle differentiation pathway. MyoD1 is expressed in myoblasts and in activated satellite cells, but not in normal mature skeletal muscle or in quiescent satellite cells; Anti MyoD1 is therefore used to identify cells that are committed to myogenesis. Anti-MyoD1 is also utilized as a biomarker for rhabdomyosarcomas, a malignant soft tissue neoplasm, often as part of a panel also including Anti-Myogenin and Anti-Desmin.

• IHC630-MyoD1 Datasheet-RUO

• MSDS

CLONE:
IHC630

ISOTYPE:


HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Fetal muscle, rhabdomyosarcoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
RUO