GeneAb™ Nerve Growth Factor Receptor (NGFR) [IHC637] on Brain
GeneAb™ Nerve Growth Factor Receptor (NGFR) [IHC637] on Brain
Nerve Growth Factor Receptor (NGFR)

CAT. NO. IHC637
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Description

Nerve Growth Factor Receptor (NGFR), also known as p75, P-75NTR, or CD271, is a neurotrophin receptor belonging to the tumour necrosis factor receptor family. It is expressed mainly in Schwann cells and neurons, as well as a number of other non-neuronal cell types, and is also expressed in melanocytes, melanomas, neuroblastomas, pheochromocytomas, neurofibromas, neurotized nevi (type C melanocytes), and other neural crest cell or tumour derivatives. It has been suggested that NGFR may act as a tumour suppressor indicated in prostate and urothelial cancer, and Anti-NGFR is often used in adjunct with S100, to aid in the diagnosis of desmoplastic and neurotrophic malignant melanomas. Anti-NGFR is also useful as an aid in the diagnosis of breast malignancy, as the antibody labels the myoepithelial cells of breast ducts and intralobular fibroblasts of breast ducts.

Documents
DATASHEETS
OTHERS
Specifications

CLONE:
IHC637

ISOTYPE:
IgG1, kappa

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Breast

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVD


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