![GeneAb™ NTRK [IHC707] on NTRK fusion cell line positive control and 293 negative cell line control.](/images/product/original/NTRK-IHC707-Fusion-NTRK-pos-neg-2.jpg)
GeneAb™ NTRK [IHC707] on NTRK fusion cell line positive control and 293 negative cell line control.
Neurotrophic tyrosine kinase receptor (NTRK) is a family of 3 proto-oncogenes including NTRK1, NTRK2, and NTRK3. NTRK gene fusions have been reported in a variety of tumor types, which are involved in biological processes such as neuronal survival, differentiation, and plasticity under physiological circumstances. Recently, the FDA has approved Entrectinib for patients with NTRK fusions, thus testing for NTRK fusions identifies patients who may be candidates for NTRK inhibitor therapy.
CLONE:
IHC707
ISOTYPE:
IgG, kappa (Rab)
HOST SPECIES:
Rabbit
CLONALITY:
Monoclonal
POSITIVE CONTROL:
NTRK fusion + Carcinoma
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR