GeneAb™ Nanog [IHC634] on Seminoma
Nanog is a homeoprotein that functions with pluripotent factors, such as Oct-4 and SOX2, to maintain embryonic stem cell pluripotency. Expression of this protein has been noted in seminoma, dysgerminoma, embryonal carcinoma, and other undifferentiated germ cell tumours, while Nanog expression is absent in normal adult organ tissues. Anti-Nanog may be useful in distinguishing between undifferentiated germ cell tumours and non-germ cell tumours.
CLONE:
IHC634
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Seminoma
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVD