GeneAb™ PD-L1 [IHC411] on Lung
GeneAb™ PD-L1 [IHC411] on Lung
PD-L1

CAT. NO. IHC411
FORMAT
VOLUME
PRICE
N/A
QUANTITY
<
1
<
*The listed price is an estimate only.
Description

Programmed Death-Ligand 1 (PD-L1), CD274, or B7 Homolog 1 (B7-H1), is a transmembrane protein involved in suppressing the immune system and rendering tumour cells resistant to lysis through binding of the Programmed Death-1 (PD-1) receptor. Overexpression of PD-L1 may allow cancer cells to evade the actions of the host immune system. In renal cell carcinoma, upregulation of PD-L1 has been linked to increased tumour aggressiveness and risk of death. When considered in adjunct with CD8+ tumour-infiltrating lymphocyte density, expression levels of PD-L1 may be a useful predictor of multiple cancer types, including stage III non-small-cell lung cancer, hormone receptor negative breast cancer, and sentinel lymph node melanoma.

Documents
DATASHEETS
OTHERS
Specifications

CLONE:
IHC411

ISOTYPE:
IgG

HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil, Lung Adenocarcinoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
RUO


Customer Reviews
No customer reviews.