Special AT-Rich Sequence-Binding Protein 2 (SATB2), also known as DNA-binding protein SATB2, is a protein involved in transcriptional regulation and chromatin remodeling. It has been identified as a potentially useful marker for neuroendocrine neoplasms or carcinomas of the colon and rectum, as well as for detecting osteoblastic differentiation in benign and malignant mesenchymal tumours. When used in combination with Cytokeratin 20 and Cadherin-17, SATB2 is able to help identify the large majority of colorectal carcinomas. Anti-SATB2 is useful for identifying colorectal carcinomas when working on a tumour of unknown origin, since upper gastrointestinal carcinomas, pancreatic ductal carcinomas, ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origins are all typically negative for SATB2.

• IHC095-SATB2 Datasheet-RUO

• MSDS

CLONE:
IHC095

ISOTYPE:


HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Colon Adenocarcinoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
RUO