![GeneAb™ SOX-2 [IHC665] on Lung](/images/product/original/SOX2-IHC665-Lung.jpg)
GeneAb™ SOX-2 [IHC665] on Lung
SOX-2, also known as SRY (Sex Determining Region Y)-Box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX-2 IVD antibody is used to detect melanoma, testicular germ cell tumour, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX-2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX-2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma.
CLONE:
IHC665
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Lung Squamous Carcinoma
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR