SOX-2, also known as SRY (Sex Determining Region Y)-Box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX-2 IVD antibody is used to detect melanoma, testicular germ cell tumour, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX-2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX-2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma.

• SOX-2 Datasheet IVDR

• MSDS

CLONE:
IHC665

ISOTYPE:
IgG1

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Lung Squamous Carcinoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR