Wilms' Tumour Protein (WT1) is a transcription factor involved in the development of the urogenital system. Anti-WT1 is utilized in the differential diagnosis of pulmonary malignancies (nuclei staining) and small round cell tumours. Ewing's sarcomas, primitive neuroectodermal tumours, neuroblastomas, rhabdomyosarcomas, and rhabdoid tumours do not stain with Anti-WT1, but cytoplasmic staining may be observed. Although lung adenocarcinomas do not exhibit nuclear staining with Anti-WT1, the antibody may stain the cytoplasm. Anti-WT1 also stains serous ovarian carcinomas, but does not stain mucinous carcinomas of the ovary and pancreatobiliary carcinomas.

• WT1 Datasheet IVDR

• MSDS

CLONE:
IHC685

ISOTYPE:
IgG1

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Ovarian Serous Carcinoma, Mesothelioma, Kidney, Testes

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR