![GeneAb™ c-Myc [IHC448] on Tonsil](/images/product/original/c-Myc-IHC448-Tonsil.jpg)
GeneAb™ c-Myc [IHC448] on Tonsil
c-Myc is a phosphoprotein involved with cell proliferation and differentiation. It is a useful marker for differentiation between Burkitt's lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) since, despite morphological similarities between the two B-cell lymphomas, Anti-c-Myc stains all BL and only a few DLBCL cases. A panel of antibodies against c-Myc, CD10, BCL2, and Ki-67 is useful for cases where Myc FISH analysis is warranted or can be omitted. Nuclear c-Myc overexpression is common in luminal cells of prostate intraepithelial neoplasia, many primary carcinomas, and metastatic disease.
CLONE:
IHC448
ISOTYPE:
IgG
HOST SPECIES:
Rabbit
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Tonsil
DILUTION RANGE:
INTENDED USE/REG. STATUS:
IVDR