GeneAb™ hENT1 [IHC595] on Thyroid Cancer
The Human Equilibrative Nucleoside Transporter 1 (hENT1) mediates the cellular uptake of physiologic nucleosides, including adenosine, as well as many anti-cancer drugs including gemcitabine, cytarabine, and decitabine. Deficiency of hENT1 can lead to resistance of such drugs, and the abundance of hENT1 protein in the plasma membrane is a major indicator of the efficiency and clinical outcome of these anti-cancer nucleosides.
CLONE:
IHC595
ISOTYPE:
IgG1
HOST SPECIES:
Mouse
CLONALITY:
Monoclonal
POSITIVE CONTROL:
Adrenal Cortex, Kidney, Thyroid, Tonsil, Normal Pancreas
DILUTION RANGE:
INTENDED USE/REG. STATUS: