p57^Kip2, also known as p57, is a tumour suppressor protein that causes cell cycle arrest at G1 by binding to G1 cyclin-CDK complexes. The p57^Kip2 gene is a potential tumour suppressor target as the gene is located in a chromosomal region implicated in sporadic cancers, Wilms' tumour, and Beckwith Wiedemann syndrome. Anti-p57^Kip2 labels many cytotrophoblast nuclei and stromal cells in normal placenta, and is useful in differentiating between complete hydatidiform mole and partial hydatidiform mole or hydropic abortion.

• p57 (Kip2) Datasheet IVDR

• MSDS

CLONE:
IHC057

ISOTYPE:
IgG2b

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Placenta

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR