GeneAb™

Annexin A1

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$135.00

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Cat. No.

IHC512-100

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Description

Annexin A1 (ANXA1) is a membrane protein that plays a role in innate and adaptive immunity by controlling the biosynthesis of inflammation, prostaglandins, and leukotriene mediators. This target is overexpressed in 97% of all samples from patients with with hairy cell leukemia, and is absent in other B-cell lymphomas. High ANXA1 expression is frequently associated with advanced stage esophageal and esophagogastric junction adenocarcinoma, and is also linked to advanced and metastatic disease states.

Specifications

Clone IHC512
Source Mouse Monoclonal
Positive Control Hairy Cell Leukemia
Dilution Range 1:100 - 1:200

References

  1. Tiacci E, et al. N Eng J Med. 2011; 364:2305-2315.
  2. Wang K, et al. Clin Cancer Res. 2006; 12:4598-4604.