GeneAb™

BCL6

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$100.00

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Cat. No.

IHC515-100

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Description

B-Cell Lymphoma 6 (BCL6) is a zinc finger transcription factor. BCL6 expression is seen in follicular lymphomas, Burkitt's lymphomas, angioimmunoblastic T-cell lymphoma, and nodular lymphocyte-predominant Hodgkin's lymphoma. Together with BCL2, BCL6 is often used to distinguish neoplastic follicles from those in benign hyperplasia, and to aid in the classification of mantle cell lymphomas and nodular lymphocyte-predominant Hodgkin's lymphoma.

Specifications

Clone IHC515
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Ye BH, et al. Science. 1993; 262:747–50.
  2. Johnston RJ, et al. Science. 2009; 325:1006–10.
  3. Dogan A, et al. Am J Surg Pathol. 2000; 24:846-852.
  4. Falini B, et al. Blood. 1996; 87:465-71.
  5. Kraus MD, et al. Am J Surg Pathol. 2000; 24:1068-78.