GeneAb™

BRCA1

(In the pipeline)

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$135.00

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Cat. No.

IHC401-100

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Description

BRCA1 (Breast-Cancer susceptibility gene 1) is a tumor suppressor protein involved in a number of cellular processes, including DNA repair and transcriptional regulation in response to DNA damage. Mutations and deficiencies in BRCA1 have been linked to poor prognosis in breast cancer, therefore Anti-BRCA1 is used for rapid screening of the marker.

Specifications

Clone IHC401
Source Mouse Monoclonal
Positive Control Breast Carcinoma
Dilution Range 1:100 - 1:200

References

  1. Ribeiro-Silva A, et al. Histopathology. 2005: 47:458-66.
  2. Ansquer Y, et al. Anticancer Res. 2005: 25:4535-41.
  3. Kurebayashi J, et al. Anticancer Res. 2006: 26:695-701.
  4. Jarvis EM, et al. Cancer Genet Cytogenet. 1998: 101:109-15.
  5. Yoshida K, et al. Cancer Sci. 2004; 95:866-71.