GeneAb™

CD138

Select Format:

Select Volume:

Price:

$125.00

Quantity:

Cat. No.

IHC138-100

Inquire

Description

Cluster of differentiation 138 (CD138), also known as Syndecan-1, is a transmembrane glycoprotein present on the surface of B-cells during late stage differentiation. Anti-CD138 is used to differentiate marginal zone lymphoma from lymphoplasmacytic lymphoma. ALK+ Large B-Cell Lymphoma (LBCL) commonly stains positively for CD138, but not for CD20 and CD79a. Anti-CD138 reacts positively with HHV8-associated primary effusion lymphoma that lack B-cell markers. CD138 is also a useful marker for identifying and enumerating benign, reactive, or malignant plasma cells from the bone marrow biopsy samples.

Specifications

Clone IHC138
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Chilosi M, et al. Mod Pathol. 1999; 12:1101-6.
  2. Sebestyén A, et al. Br J Haematol. 1999; 104:412-9.
  3. Bayer-Garner IB, et al. Mod Pathol. 2001; 14:1052-8.
  4. Said J, et al. WHO Press, Geneva, Switzerland. 261.
  5. O’Connell FP, et al. Am J Clin Pathol. 2004; 121:254-63.
  6. Colomo L, et al. Am J Surg Pathol. 2004; 28:736-47.
  7. Carbone A, et al. Blood. 1998; 91:747-55.