Cluster of Differentiation 16 (CD16) is a receptor on natural killer cells, neutrophils, monocytes, and macrophages. CD16 binds the Fc portion of antibodies to activate these immune cells. CD16 staining is useful in the differential diagnosis of hepatosplenic gamma delta T-cell lymphoma and gamma delta T-cell large granular lymphocyte leukemia from mucosal and cutaneous gamma delta T-cell lymphoma. Likely due to dysgranulopoiesis, granulocytes with myelomonocytic leukemia have decreased CD16 expression in comparison to granulocytes with chronic myelogenous leukemia and control bone marrow biopsies.

• Please email us to request the datasheet.

• MSDS

CLONE:
IHC528

ISOTYPE:


HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR