GeneAb™

CD16

(In the pipeline)

Select Format:

Select Volume:

Price:

$140.00

Quantity:

Cat. No.

IHC528-100

Inquire

Description

Cluster of differentiation 16 (CD16) is a receptor on natural killer cells, neutrophils, monocytes, and macrophages that binds the Fc portion of antibodies to activate these immune cells. CD16 staining is useful in the differential diagnosis of hepatosplenic gamma delta T-cell lymphoma and gamma delta T-cell large granular lymphocyte leukemia from mucosal and cutaneous gamma delta T-cell lymphoma. Likely due to dysgranulopoiesis, granulocytes with myelomonocytic leukemia have decreased CD16 expression in comparison to granulocytes with chronic myelogenous leukemia and control bone marrow biopsies.

Specifications

Clone IHC528
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Gibson SE, et al. Hum Pathol. 2011; 42:679-87.
  2. Qubaja M, et al. Virchows Arch. 2009; 454:411-9.