GeneAb™

CD2

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$205.00

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Cat. No.

IHC531-100

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Description

Cluster of differentiation 2 (CD2) is a useful early T-cell lineage restricted antigen that is present in T-cell differentiation. As a pan-T-cell marker, CD2 staining is used for recognizing practically all normal T-cells, but may be deleted in some T-cell neoplasms. Since CD2 is present in most precursor and mature T-cell leukemias and lymphomas, it is useful in the evaluation of lymphoid malignancies. By using CD2 and CD25 staining, the recognition of systemic mastocytosis and mastocytic leukemia is supported.

Specifications

Clone IHC531
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Went P, et al. J Clin Oncol. 2006; 24:2472-2479.
  2. Aguilera NS, et al. Arch Pathol Lab Med. 2006; 130:1772-9.
  3. Barrionuevo C, et al. Appl Immunohistochem Mol Morphol. 2007; 15:38-44.
  4. Bovenschen HJ, et al. Br J Dermatol. 2005; 153:72-8.
  5. Foon KA, et al. Blood 1986; 68:1- 31.