GeneAb™

CD20

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$120.00

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Cat. No.

IHC532-100

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Description

Cluster of differentiation (CD20), also known as B-lymphocyte antigen, is a non-glycosylated protein expressed on the surface of normal and malignant B-cells, which functions in chemokine signaling and microenvironmental interactions of B-cells. Anti-CD20 stains a minority of Reed-Sternberg cells with Hodgkin’s disease. Since CD20 does not stain T-cell malignancies, it is a very useful marker for B-cell lymphomas. CD20 is also not reactive on non-hematopoietic neoplasms.

Specifications

Clone IHC532
Source Mouse Monoclonal
Positive Control Tonsil, Lymph Node
Dilution Range 1:100 - 1:200

References

  1. Ishii Y, et al. Clin Exp Immuno. 1984; 58:183-92.
  2. Davey FR, et al. Am J Pathol. 1987; 129:54-63.
  3. Mason DY. Am J Pathol. 1987; 128:1-4.
  4. Tzankov A, et al. Clin Cancer Res. 2003; 9:1381-6.
  5. Browne P, et al. Am J Clin Pathol. 2003; 120:767-77.