GeneAb™

CD22

Select Format:

Select Volume:

Price:

$140.00

Quantity:

Cat. No.

IHC022-100

Inquire

Description

Cluster of differentiation 22 (CD22) is a glycoprotein that appears on the cell membrane of B-cells and the cytoplasm of late pro- and early pre-B lymphocytes. Anti-CD22 is a useful pan-B reagent that allows for the identification of neoplastic and normal B lymphocytes in the peripheral blood. CD22 is overexpressed in hairy cell leukemia. Expression is only present in the late stages of B-lymphocyte differentiation, and therefore may support the identification of mature B-cell leukemia. Some studies have suggested that CD22 may be involved in metastasis of lung cancer cells.

Specifications

Clone IHC022
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Abdel-Ghafar A, et al. Hematol Rep. 2012; 4:e3
  2. Tuscano J, et al. Cancer Res. 2012; 72:5556-65.
  3. Shao H, et al. Leuk Res. 2013; 37:401-409.