GeneAb™

CD30

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$125.00

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Cat. No.

IHC030-100

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Description

Cluster of differentiation 30 (CD30) is a transmembrane cytokine receptor expressed by activated T and B cells. It is present on Reed-Sternberg cells in Hodgkin’s lymphoma, most anaplastic large cell lymphomas, embryonal carcinomas, and primary cutaneous CD30 positive T-cell lymphoproliferative disorders. B-cell lymphomas are sometimes stained by Anti-CD30. Lymphomas exhibit Golgi zone accentuation when stained with Anti-CD30, while embryonal carcinomas produce membranous stains.

Specifications

Clone IHC030
Source Mouse Monoclonal
Positive Control Classic Hodgkin Lymphoma, Lymphoma
Dilution Range 1:100 - 1:200

References

  1. Schwarting R, et al. Blood. 1989; 74:1678-1689.
  2. George DH, et al. Am J Surg Pathol. 2003; 27:487-93.
  3. Hedvat CV, et al. Hum Pathol. 2002; 33:968-74.
  4. Schneider C, et al. Leuk Lymphoma. 2002; 43:1355–66.
  5. Dürkop H, et al. Cell. 1992; 68:421-7
  6. Gorczyca W, et al. Int J Oncol. 2003; 22:319–24.