Cluster of Differentiation 7 (CD7) is an antigen expressed in immature and mature T-lymphocytes, thymocytes, peripheral blood T-cells, natural killer cells, myeloid precursors, fetal liver and bone marrow, a small subpopulation of normal B-cells, and malignant B-cells. The antigen belongs to the immunoglobulin gene superfamily, and plays an important role in T-cell interactions and T-cell/B-cell interactions during early lymphoid development. CD7 is indicated as a marker for acute myelogenous leukemia and chronic myelogenous leukemia, and for neoplastic proliferations such as T-cell acute lymphoblastic leukemia/lymphoma. Anti-CD7, when used in adjunct with Anti-CD4, is useful for differentiating mycosis fungoides or Sézary syndrome (both cutaneous T-cell lymphomas) from benign dermatoses.

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• MSDS

CLONE:
IHC541

ISOTYPE:


HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil, Peripheral T-Cell Lymphoma

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVDR