GeneAb™

Cytokeratin 17

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$125.00

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Cat. No.

IHC017-100

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Description

Cytokeratin 17 (CK17) is part of the intermediate filament, and is present in basal cells and myoepithelial cells. Cytokeratin 17 is a useful marker for identifying breast cancers of basal nature, as well as squamous cell carcinoma. Anti-Cytokeratin 17 can help differentiate cholangiocarcinoma (positive stain) from hepatocellular carcinoma (negative stain). A panel of Anti-MUC1 and Anti-Cytokeratin 17 can be used for differentiation between Cytokeratin 17(+) pancreatobiliary adenocarcinoma from Cytokeratin 17(-) extra-pancreatobiliary nonmucinous adenocarcinoma.

Specifications

Clone IHC017
Source Mouse Monoclonal
Positive Control Immature Cervical Metaplasia, Breast
Dilution Range 1:100 - 1:200

References

  1. Regauer S, et al. Histopathology. 2007; 50:629-35.
  2. Martens JE, et al. Anticancer Res. 2004; 24:771-5.
  3. Escobar-Hoyos LF, et al. Mod Pathol. 2014; 27:621-30.
  4. Kitamura R. et al. J Cancer Res Clin Oncol. 2012; 138:1299-1310.