GeneAb™

Cytokeratin 19

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$135.00

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Cat. No.

IHC019-100

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Description

Cytokeratin 19 (CK19) forms intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue and provides mechanical support. Anti-Cytokeratin 19 stains epithelia and epithelial malignancies such as carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Cytokeratin 19 is a useful marker for distinguishing hepatocellular carcinoma from intrahepatic cholangiocarcinoma. This differentiation is improved when stained in combination with Cytokeratin 7, CAM5.2l, Ber-EP4/MOC31, HepPar1 and TTF1. Cytokeratin 19 staining can also be used to recognize thyroid papillary carcinomas.

Specifications

Clone IHC019
Source Mouse Monoclonal
Positive Control Bladder, Colon Carcinoma, Colon, Thyroid Carcinoma
Dilution Range 1:100 - 1:200

References

  1. Jain R, et al. Appl Immunohistochem Mol Morphol. 2010; 18:9-15.
  2. Rosai J. Tumori. 2003; 89:517-9.
  3. de Matos LL, et al. Diagn Pathol. 2012; 7:97.